John Millman punishes under-par Roger Federer in stunning US Open upset

Novak Djokovic and Richard Gasquet

Roger Federer failed to cope with stifling conditions at the U.S. Open on Monday and suffered a shock 3-6 7-5 7-6 (7) 7-6 (3) defeat to unseeded Australian John Millman in the last 16.

Hours before, Djokovic left the court for a medical timeout - the second time during the tournament he's sought help from a doctor because of harsh weather - during what would become an otherwise straightforward 6-3, 6-4, 6-3 victory over 68th-ranked Joao Sousa of Portugal.

It's only the second time in Federer's past 14 appearances at the US Open that he has lost before the quarterfinals.

Millman confessed to being in "disbelief" while he acknowledged that the second seed was well below par, but he was delighted with the fight he showed to turn the contest on its head, having been a set and a break down.

Kohlschreiber was denied again in his fifth attempt to win a fourth-round match at the U.S. Open.

Seventh-seeded Cilic, who needed eight match points in a five-set marathon against Australian teenager Alex de Minaur spilled into Sunday morning survived some tense moments to get past 10th-ranked Belgian David Goffin 7-6 (8/6), 6-2, 6-4.

It was the 37-year-old's earliest loss at a slam since the Australian Open in 2015 and the first time he has ever lost to a player ranked outside the top 50 in NY.

"I've got a lot of respect for Roger".

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Next up for Millman is a quarter-final match-up against Novak Djokovic, and Federer said the sixth seed will have a fight on his hands.

Djokovic did his part improving his flawless NY record in fourth round contests to 11-0 leaving it to Federer, who will take on Australian John Millman in the late contest on Arthur Ashe Stadium court to give the fans what would be a hotly anticipated match-up.

Kei Nishikori is into the quarterfinals of his return to the U.S. Open.

Nishikori missed the U.S. Open past year because of a right wrist injury.

Second seed Federer, who had not dropped a set in his first three matches, was uncharacteristically sloppy, committing 77 unforced errors and 10 double faults while landing just 49 percent of his first serves.

Madison Keys eased into the quarter-finals of the US Open with a 6-1 6-3 victory over Slovakia's Dominika Cibulkova.

Kei Nishikori will be hoping to make another deep run at his most successful grand slam event after he outclassed Philipp Kohlschreiber 6-3 6-2 7-5 to reach the quarter-finals of the US Open on another scorchingly hot day in NY.

Djokovic has sweated his way to a 6-3, 6-4, 6-3 fourth round win over Joao Sousa as the heat returned to the US Open.

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